Developmental interactions between thalamus and cortex: a true love reciprocal story

12-P009 Building reciprocal projections between the cerebral cortex and the dorsal thalamus

The monosynaptic trigeminal neural circuit in the head is essential for eating and suckling in mammals. Little is known about how this circuit forms and in particular, almost nothing is known about the development of the proprioceptive sensory component, the mesencephalic trigeminal nucleus (MTN). It is unclear what the cell types are that form the MTN, the molecular signals that direct its spe...

Role of Emx2 in the development of the reciprocal connectivity between cortex and thalamus.

Emx2 knockout mice appear to show a shift in the areal identity in the cerebral cortex , which is matched with altered distribution of thalamocortical projections (Bishop et al. [2000] Science 288:344-349; Mallamaci et al. [2000] Nat Neurosci. 3:679-686) [corrected]. We have examined the early establishment of these projections to understand how the altered Emx2 expression results in changes in...

Reciprocal Connections Between Cortex and Thalamus Contribute to Retinal Axon Targeting to Dorsal Lateral Geniculate Nucleus.

The dorsal Lateral Geniculate Nucleus (dLGN) is the primary image-forming target of the retina and shares a reciprocal connection with primary visual cortex (V1). Previous studies showed that corticothalamic input is essential for the development of thalamocortical projections, but less is known about the potential role of this reciprocal connection in the development of retinal projections. He...

A true case story

Autism is not generally recognized as a condition which can be bio-medically influenced. As of today, there are no biomarkers for autism that are recognized by traditional medicine. Treating autism medically is a difficult and hopeless task according to official guidelines (even though it is seldom written in official documents). Parents of many children who have or had an ASD diagnosis have wi...

Privacy and Markets: A Love Story